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Mode of Action of Chemical Agents
Chemical agents act on microorganisms by:
- They may damage the lipids and proteins of the cytoplasmic membrane of microorganisms.
- They may denature microbial enzymes and other proteins usually by disrupting the hydrogen and disulfide bonds that give the protein its 3-D shape. This blocks metabolism function.
Modes Of Action
Mechanisms Of Resistance:-
- Most antimicrobials fall into one of four main categories, based on their site of activity.
- These include inhibition of cell wall synthesis, protein synthesis, nucleic acid synthesis, or disruption of cell membrane integrity.
There are a number of factors which influence the antimicrobial action of disinfectants and antiseptics, including:-
- The concentration of the chemical agent.
- The temperature at which the agent is being used.
- The number of microorganisms present.
- The nature of the material bearing the microorganisms.
- The chemical agent that kills bacteria is Bactericide.